MPN domain containing

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
chromatin remodeling [GO:0006338],
proteolysis [GO:0006508],
biological_process [GO:0008150],
positive regulation of transcription from RNA polymerase II promoter [GO:0045944],

Molecular Function:
molecular_function [GO:0003674],
transcription coactivator activity [GO:0003713],
thiol-dependent ubiquitin-specific protease activity [GO:0004843],
peptidase activity [GO:0008233],
metallopeptidase activity [GO:0008237],
hydrolase activity [GO:0016787],
histone binding [GO:0042393],
metal ion binding [GO:0046872],