actin related protein 2/3 complex subunit 5

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945054 IMR-90 Human YES

GO terms:

Biological Process:
smooth muscle cell migration [GO:0014909],
cell migration [GO:0016477],
orbitofrontal cortex development [GO:0021769],
maintenance of cell polarity [GO:0030011],
actin cytoskeleton organization [GO:0030036],
Arp2/3 complex-mediated actin nucleation [GO:0034314],
Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096],
neutrophil degranulation [GO:0043312],
ephrin receptor signaling pathway [GO:0048013],
actin filament network formation [GO:0051639],
membrane organization [GO:0061024],
lamellipodium organization [GO:0097581],
regulation of actin filament polymerization [GO:0030833],

Molecular Function:
structural constituent of cytoskeleton [GO:0005200],
protein binding [GO:0005515],
actin filament binding [GO:0051015],
actin binding [GO:0003779],

Cellular Component:
extracellular region [GO:0005576],
nucleus [GO:0005634],
cytoplasm [GO:0005737],
endosome [GO:0005768],
cytosol [GO:0005829],
Arp2/3 protein complex [GO:0005885],
focal adhesion [GO:0005925],
actin cytoskeleton [GO:0015629],
lamellipodium [GO:0030027],
growth cone [GO:0030426],
secretory granule lumen [GO:0034774],
site of double-strand break [GO:0035861],
extracellular exosome [GO:0070062],
ficolin-1-rich granule lumen [GO:1904813],
cytoskeleton [GO:0005856],
cell projection [GO:0042995],
neuron projection [GO:0043005],