actin related protein 2/3 complex subunit 4

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945054 IMR-90 Human YES

GO terms:

Biological Process:
actin filament polymerization [GO:0030041],
Arp2/3 complex-mediated actin nucleation [GO:0034314],
Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096],
actin nucleation [GO:0045010],
ephrin receptor signaling pathway [GO:0048013],
membrane organization [GO:0061024],
regulation of actin filament polymerization [GO:0030833],

Molecular Function:
structural constituent of cytoskeleton [GO:0005200],
protein binding [GO:0005515],
enzyme binding [GO:0019899],
protein binding, bridging [GO:0030674],
actin filament binding [GO:0051015],
actin binding [GO:0003779],

Cellular Component:
nucleus [GO:0005634],
cytosol [GO:0005829],
Arp2/3 protein complex [GO:0005885],
site of double-strand break [GO:0035861],
cell projection [GO:0042995],
extracellular exosome [GO:0070062],
cytoplasm [GO:0005737],
cytoskeleton [GO:0005856],
actin cytoskeleton [GO:0015629],