matrix metallopeptidase 17

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31242426 HFF-2  Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
kidney development [GO:0001822],
proteolysis [GO:0006508],
extracellular matrix organization [GO:0030198],
collagen catabolic process [GO:0030574],
drinking behavior [GO:0042756],
positive regulation of catalytic activity [GO:0043085],

Molecular Function:
metalloendopeptidase activity [GO:0004222],
enzyme activator activity [GO:0008047],
zinc ion binding [GO:0008270],
metalloaminopeptidase activity [GO:0070006],
peptidase activity [GO:0008233],
metallopeptidase activity [GO:0008237],
hydrolase activity [GO:0016787],
metal ion binding [GO:0046872],

Cellular Component:
plasma membrane [GO:0005886],
extracellular matrix [GO:0031012],
anchored component of membrane [GO:0031225],
extracellular region [GO:0005576],
membrane [GO:0016020],