ARNT

aryl hydrocarbon receptor nuclear translocator

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
30967634 HUVEC Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
31983656 MSC Human YES

GO terms:

Biological Process:
response to hypoxia [GO:0001666],
embryonic placenta development [GO:0001892],
positive regulation of endothelial cell proliferation [GO:0001938],
transcription, DNA-templated [GO:0006351],
xenobiotic metabolic process [GO:0006805],
positive regulation of vascular endothelial growth factor production [GO:0010575],
cell differentiation [GO:0030154],
intracellular receptor signaling pathway [GO:0030522],
positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949],
positive regulation of protein sumoylation [GO:0033235],
regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619],
positive regulation of erythrocyte differentiation [GO:0045648],
positive regulation of glycolytic process [GO:0045821],
positive regulation of transcription, DNA-templated [GO:0045893],
positive regulation of transcription from RNA polymerase II promoter [GO:0045944],
positive regulation of hormone biosynthetic process [GO:0046886],
regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418],
regulation of transcription, DNA-templated [GO:0006355],
response to toxic substance [GO:0009636],

Molecular Function:
RNA polymerase II core promoter proximal region sequence-specific DNA binding [GO:0000978],
RNA polymerase II transcription factor activity, sequence-specific DNA binding [GO:0000981],
core promoter proximal region sequence-specific DNA binding [GO:0000987],
transcription factor activity, sequence-specific DNA binding [GO:0003700],
transcription coactivator activity [GO:0003713],
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding [GO:0004879],
protein binding [GO:0005515],
transcription factor binding [GO:0008134],
aryl hydrocarbon receptor binding [GO:0017162],
protein homodimerization activity [GO:0042803],
sequence-specific DNA binding [GO:0043565],
protein heterodimerization activity [GO:0046982],
sequence-specific double-stranded DNA binding [GO:1990837],
DNA binding [GO:0003677],
macromolecular complex binding [GO:0044877],
protein dimerization activity [GO:0046983],

Cellular Component:
nuclear chromatin [GO:0000790],
nucleus [GO:0005634],
nucleoplasm [GO:0005654],
cytoplasm [GO:0005737],
nuclear body [GO:0016604],
RNA polymerase II transcription factor complex [GO:0090575],
transcription factor complex [GO:0005667],