MIR29B1

microRNA 29b-1

Link to human ortholog


Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29958242 Primary cardiomyocyte derived from heart Rat NO
31767948 HeLa, NIH/3T3 Human, mouse YES

GO terms:

Biological Process:
negative regulation of cytokine-mediated signaling pathway [GO:0001960],
negative regulation of cell proliferation [GO:0008285],
positive regulation of gene expression [GO:0010628],
negative regulation of gene expression [GO:0010629],
negative regulation of epithelial to mesenchymal transition [GO:0010719],
positive regulation of triglyceride biosynthetic process [GO:0010867],
positive regulation of cell migration [GO:0030335],
negative regulation of cell migration [GO:0030336],
negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512],
negative regulation of collagen biosynthetic process [GO:0032966],
gene silencing by miRNA [GO:0035195],
miRNA mediated inhibition of translation [GO:0035278],
positive regulation of apoptotic process [GO:0043065],
negative regulation of MAPK cascade [GO:0043409],
regulation of DNA methylation [GO:0044030],
positive regulation of fat cell differentiation [GO:0045600],
negative regulation of epithelial cell proliferation [GO:0050680],
negative regulation of protein secretion [GO:0050709],
negative regulation of protein kinase B signaling [GO:0051898],
regulation of blood vessel remodeling [GO:0060312],
negative regulation of circulating fibrinogen levels [GO:0061754],
negative regulation of canonical Wnt signaling pathway [GO:0090090],
cellular response to virus [GO:0098586],
negative regulation of extracellular matrix assembly [GO:1901202],
negative regulation of NIK/NF-kappaB signaling [GO:1901223],
positive regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902110],
negative regulation of mesenchymal stem cell proliferation [GO:1902461],
negative regulation of oxidative stress-induced cell death [GO:1903202],
negative regulation of cellular response to transforming growth factor beta stimulus [GO:1903845],
regulation of aorta morphogenesis [GO:1903847],
negative regulation of collagen fibril organization [GO:1904027],
negative regulation of matrix metallopeptidase secretion [GO:1904465],
positive regulation of metalloendopeptidase activity [GO:1904685],
regulation of epithelium regeneration [GO:1905041],
negative regulation of metallopeptidase activity [GO:1905049],
positive regulation of canonical Wnt signaling pathway involved in osteoblast differentiation [GO:1905241],
negative regulation of intestinal epithelial cell development [GO:1905299],
negative regulation of G1/S transition of mitotic cell cycle [GO:2000134],

Molecular Function:
mRNA 3'-UTR binding [GO:0003730],
mRNA binding involved in posttranscriptional gene silencing [GO:1903231],

Cellular Component:
extracellular space [GO:0005615],
nucleus [GO:0005634],
cytoplasm [GO:0005737],
mitochondrion [GO:0005739],
extracellular exosome [GO:0070062],
extracellular vesicle [GO:1903561],