ARL8B

ADP ribosylation factor like GTPase 8B

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
28844647 BJ, WI-38, IMR-90, MRC-5, HFF, HCA57 Skin, Lung Human YES
31945125 Primary astrocytes derived from brain Human YES
31983656 MSC Human YES

GO terms:

Biological Process:
cell cycle [GO:0007049],
chromosome segregation [GO:0007059],
anterograde axonal transport [GO:0008089],
protein transport [GO:0015031],
endosomal transport [GO:0016197],
lysosome localization [GO:0032418],
cell division [GO:0051301],

Molecular Function:
GTPase activity [GO:0003924],
protein binding [GO:0005515],
GTP binding [GO:0005525],
GDP binding [GO:0019003],
alpha-tubulin binding [GO:0043014],
beta-tubulin binding [GO:0048487],
nucleotide binding [GO:0000166],

Cellular Component:
cytoplasm [GO:0005737],
lysosomal membrane [GO:0005765],
vacuolar membrane [GO:0005774],
membrane [GO:0016020],
midbody [GO:0030496],
late endosome membrane [GO:0031902],
synapse [GO:0045202],
spindle midzone [GO:0051233],
extracellular exosome [GO:0070062],
axon cytoplasm [GO:1904115],
lysosome [GO:0005764],
endosome [GO:0005768],
cytoskeleton [GO:0005856],
cell junction [GO:0030054],
axon [GO:0030424],
cell projection [GO:0042995],