MIR199A1

microRNA 199a-1

Link to human ortholog


Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
32158519 HUVEC Human YES

GO terms:

Biological Process:
re-entry into mitotic cell cycle [GO:0000320],
negative regulation of receptor internalization [GO:0002091],
positive regulation of cytosolic calcium ion concentration [GO:0007204],
negative regulation of autophagy [GO:0010507],
positive regulation of endothelial cell migration [GO:0010595],
negative regulation of cardiac muscle cell apoptotic process [GO:0010667],
negative regulation of low-density lipoprotein particle clearance [GO:0010989],
positive regulation of TOR signaling [GO:0032008],
negative regulation of hepatocyte growth factor production [GO:0032686],
gene silencing by miRNA [GO:0035195],
negative regulation of nitric oxide biosynthetic process [GO:0045019],
regulation of angiogenesis [GO:0045765],
positive regulation of angiogenesis [GO:0045766],
positive regulation of protein kinase B signaling [GO:0051897],
regulation of cardiac muscle cell proliferation [GO:0060043],
negative regulation of cardiac muscle cell proliferation [GO:0060044],
positive regulation of cardiac muscle cell proliferation [GO:0060045],
cell growth involved in cardiac muscle cell development [GO:0061049],
positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051],
negative regulation of cell growth involved in cardiac muscle cell development [GO:0061052],
positive regulation of lung blood pressure [GO:0061766],
negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051],
negative regulation of vascular endothelial growth factor signaling pathway [GO:1900747],
positive regulation of cardiac muscle hypertrophy in response to stress [GO:1903244],
negative regulation of vascular endothelial growth factor production [GO:1904046],
negative regulation of matrix metallopeptidase secretion [GO:1904465],
negative regulation of metallopeptidase activity [GO:1905049],
positive regulation of cardiac muscle tissue regeneration [GO:1905180],
regulation of connective tissue replacement [GO:1905203],
positive regulation of connective tissue replacement [GO:1905205],

Molecular Function:
mRNA binding involved in posttranscriptional gene silencing [GO:1903231],

Cellular Component:
extracellular space [GO:0005615],