ARL6IP5

ADP ribosylation factor like GTPase 6 interacting protein 5

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES
31945125 Primary astrocytes derived from brain Human YES
31915373 Hheart_LV_VS healthy nan Human NO

GO terms:

Biological Process:
negative regulation of L-glutamate transport [GO:0002037],
intrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631],
negative regulation of mitochondrial membrane potential [GO:0010917],
L-glutamate transport [GO:0015813],
positive regulation of stress-activated MAPK cascade [GO:0032874],
positive regulation of apoptotic process [GO:0043065],
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280],
negative regulation of transport [GO:0051051],
regulation of neurotransmitter uptake [GO:0051580],

Molecular Function:
molecular_function [GO:0003674],
protein binding [GO:0005515],
protein C-terminus binding [GO:0008022],

Cellular Component:
endoplasmic reticulum membrane [GO:0005789],
cytoskeleton [GO:0005856],
plasma membrane [GO:0005886],
membrane [GO:0016020],
integral component of membrane [GO:0016021],
cytoplasm [GO:0005737],
endoplasmic reticulum [GO:0005783],