misshapen like kinase 1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
regulation of cell-matrix adhesion [GO:0001952],
protein phosphorylation [GO:0006468],
JNK cascade [GO:0007254],
chemical synaptic transmission [GO:0007268],
multicellular organism development [GO:0007275],
regulation of cell-cell adhesion [GO:0022407],
signal transduction by protein phosphorylation [GO:0023014],
microvillus assembly [GO:0030033],
regulation of cell migration [GO:0030334],
stress-activated protein kinase signaling cascade [GO:0031098],
actin cytoskeleton reorganization [GO:0031532],
activation of protein kinase activity [GO:0032147],
positive regulation of JNK cascade [GO:0046330],
protein autophosphorylation [GO:0046777],
neuron projection morphogenesis [GO:0048812],
dendrite morphogenesis [GO:0048813],
positive regulation of p38MAPK cascade [GO:1900745],
regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity [GO:2000311],
phosphorylation [GO:0016310],
negative thymic T cell selection [GO:0045060],
neuron cellular homeostasis [GO:0070050],

Molecular Function:
protein kinase activity [GO:0004672],
protein serine/threonine kinase activity [GO:0004674],
protein binding [GO:0005515],
ATP binding [GO:0005524],
nucleotide binding [GO:0000166],
kinase activity [GO:0016301],
transferase activity [GO:0016740],

Cellular Component:
cytoplasm [GO:0005737],
Golgi apparatus [GO:0005794],
cytosol [GO:0005829],
postsynaptic density [GO:0014069],
axon [GO:0030424],
dendrite [GO:0030425],
extracellular exosome [GO:0070062],
cell junction [GO:0030054],
cell projection [GO:0042995],
synapse [GO:0045202],