MGLL

monoglyceride lipase

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31155496 Primary β cells derived from pancreas Mouse YES

GO terms:

Biological Process:
lipid metabolic process [GO:0006629],
fatty acid biosynthetic process [GO:0006633],
inflammatory response [GO:0006954],
regulation of signal transduction [GO:0009966],
arachidonic acid metabolic process [GO:0019369],
triglyceride catabolic process [GO:0019433],
acylglycerol acyl-chain remodeling [GO:0036155],
acylglycerol catabolic process [GO:0046464],
regulation of inflammatory response [GO:0050727],
regulation of sensory perception of pain [GO:0051930],
monoacylglycerol catabolic process [GO:0052651],
regulation of endocannabinoid signaling pathway [GO:2000124],
fatty acid metabolic process [GO:0006631],
lipid catabolic process [GO:0016042],
regulation of axon extension [GO:0030516],
long term synaptic depression [GO:0060292],

Molecular Function:
lysophospholipase activity [GO:0004622],
protein binding [GO:0005515],
lipase activity [GO:0016298],
protein homodimerization activity [GO:0042803],
acylglycerol lipase activity [GO:0047372],
hydrolase activity [GO:0016787],
carboxylic ester hydrolase activity [GO:0052689],

Cellular Component:
nucleoplasm [GO:0005654],
endoplasmic reticulum membrane [GO:0005789],
cytosol [GO:0005829],
plasma membrane [GO:0005886],
membrane [GO:0016020],
extrinsic component of membrane [GO:0019898],
cytoplasm [GO:0005737],
axon [GO:0030424],
varicosity [GO:0043196],
synapse [GO:0045202],