MFF

mitochondrial fission factor

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
28844647 BJ, WI-38, IMR-90, MRC-5, HFF, HCA451 Skin, Lung Human YES
31431479 B16-F1 Human NO

GO terms:

Biological Process:
mitochondrial fission [GO:0000266],
release of cytochrome c from mitochondria [GO:0001836],
protein targeting to mitochondrion [GO:0006626],
mitochondrial fusion [GO:0008053],
regulation of mitochondrion organization [GO:0010821],
peroxisome fission [GO:0016559],
mitochondrial fragmentation involved in apoptotic process [GO:0043653],
mitochondrion morphogenesis [GO:0070584],
positive regulation of mitochondrial fission [GO:0090141],
positive regulation of release of cytochrome c from mitochondria [GO:0090200],
positive regulation of protein targeting to membrane [GO:0090314],
regulation of peroxisome organization [GO:1900063],
positive regulation of cardiac muscle cell apoptotic process [GO:0010666],
positive regulation of synaptic vesicle endocytosis [GO:1900244],

Molecular Function:
protein binding [GO:0005515],
identical protein binding [GO:0042802],
protein homodimerization activity [GO:0042803],
macromolecular complex binding [GO:0044877],
GTPase binding [GO:0051020],

Cellular Component:
mitochondrion [GO:0005739],
mitochondrial outer membrane [GO:0005741],
peroxisome [GO:0005777],
synaptic vesicle [GO:0008021],
integral component of mitochondrial outer membrane [GO:0031307],
integral component of mitochondrial membrane [GO:0032592],
macromolecular complex [GO:0032991],
membrane [GO:0016020],
integral component of membrane [GO:0016021],
cell junction [GO:0030054],
synaptic vesicle membrane [GO:0030672],
cytoplasmic vesicle [GO:0031410],
mitochondrial membrane [GO:0031966],
synapse [GO:0045202],