ARL2

ADP ribosylation factor like GTPase 2

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES
31945054 IMR-90 Human YES

GO terms:

Biological Process:
tubulin complex assembly [GO:0007021],
centrosome cycle [GO:0007098],
positive regulation of cell-substrate adhesion [GO:0010811],
regulation of microtubule polymerization [GO:0031113],
positive regulation of microtubule polymerization [GO:0031116],
negative regulation of GTPase activity [GO:0034260],
regulation of insulin secretion [GO:0050796],
maintenance of protein location in nucleus [GO:0051457],
bicellular tight junction assembly [GO:0070830],
cell cycle [GO:0007049],
acetylcholine transport [GO:0015870],

Molecular Function:
GTPase activity [GO:0003924],
GTPase inhibitor activity [GO:0005095],
protein binding [GO:0005515],
GTP binding [GO:0005525],
GDP binding [GO:0019003],
nucleotide binding [GO:0000166],

Cellular Component:
nucleus [GO:0005634],
nucleoplasm [GO:0005654],
nucleolus [GO:0005730],
cytoplasm [GO:0005737],
mitochondrial intermembrane space [GO:0005758],
mitochondrial matrix [GO:0005759],
Golgi apparatus [GO:0005794],
centrosome [GO:0005813],
cytosol [GO:0005829],
focal adhesion [GO:0005925],
cilium [GO:0005929],
microtubule cytoskeleton [GO:0015630],
lateral plasma membrane [GO:0016328],
mitochondrion [GO:0005739],
cytoskeleton [GO:0005856],