ARL1

ADP ribosylation factor like GTPase 1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
30659649 Primary fibroblasts derived from skin Human NO
31945125 Primary astrocytes derived from brain Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
31983656 MSC Human YES

GO terms:

Biological Process:
intracellular protein transport [GO:0006886],
Golgi organization [GO:0007030],
toxin metabolic process [GO:0009404],
vesicle-mediated transport [GO:0016192],
activation of phospholipase D activity [GO:0031584],
protein localization to Golgi apparatus [GO:0034067],
retrograde transport, endosome to Golgi [GO:0042147],
Golgi vesicle transport [GO:0048193],

Molecular Function:
GTPase activity [GO:0003924],
GTP binding [GO:0005525],
enzyme activator activity [GO:0008047],
protein domain specific binding [GO:0019904],
metal ion binding [GO:0046872],
nucleotide binding [GO:0000166],

Cellular Component:
cytoplasm [GO:0005737],
Golgi apparatus [GO:0005794],
trans-Golgi network [GO:0005802],
cytosol [GO:0005829],
trans-Golgi network membrane [GO:0032588],
membrane [GO:0016020],