AT-rich interaction domain 5A

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES
30977188 MSC Human YES

GO terms:

Biological Process:
negative regulation of transcription from RNA polymerase II promoter [GO:0000122],
regulation of transcription from RNA polymerase II promoter [GO:0006357],
innate immune response [GO:0045087],
negative regulation of transcription, DNA-templated [GO:0045892],
cellular response to estrogen stimulus [GO:0071391],
chondrocyte differentiation [GO:0002062],
immune system process [GO:0002376],
positive regulation of histone acetylation [GO:0035066],
positive regulation of transcription from RNA polymerase II promoter [GO:0045944],
cellular response to lipopolysaccharide [GO:0071222],
positive regulation of interferon-gamma secretion [GO:1902715],
positive regulation of tumor necrosis factor secretion [GO:1904469],
positive regulation of interleukin-17 secretion [GO:1905078],
positive regulation of T-helper 17 type immune response [GO:2000318],
positive regulation of T-helper 1 cell cytokine production [GO:2000556],
positive regulation of interleukin-6 secretion [GO:2000778],

Molecular Function:
transcription regulatory region sequence-specific DNA binding [GO:0000976],
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding [GO:0001227],
DNA binding [GO:0003677],
transcription corepressor activity [GO:0003714],
RNA binding [GO:0003723],
protein binding [GO:0005515],
transcription factor binding [GO:0008134],
estrogen receptor binding [GO:0030331],
sequence-specific DNA binding [GO:0043565],
retinoid X receptor binding [GO:0046965],
thyroid hormone receptor binding [GO:0046966],
androgen receptor binding [GO:0050681],
chromatin binding [GO:0003682],
RNA stem-loop binding [GO:0035613],

Cellular Component:
nucleus [GO:0005634],
nucleoplasm [GO:0005654],
nucleolus [GO:0005730],
transcription factor complex [GO:0005667],