MAPK8IP1

mitogen-activated protein kinase 8 interacting protein 1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945054 IMR-90 Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
regulation of transcription, DNA-templated [GO:0006355],
JUN phosphorylation [GO:0007258],
vesicle-mediated transport [GO:0016192],
negative regulation of JUN kinase activity [GO:0043508],
regulation of JNK cascade [GO:0046328],
positive regulation of JNK cascade [GO:0046330],
regulation of CD8-positive, alpha-beta T cell proliferation [GO:2000564],
negative regulation of intrinsic apoptotic signaling pathway [GO:2001243],
signal transduction [GO:0007165],
negative regulation of apoptotic process [GO:0043066],
negative regulation of JNK cascade [GO:0046329],

Molecular Function:
protein kinase inhibitor activity [GO:0004860],
MAP-kinase scaffold activity [GO:0005078],
protein binding [GO:0005515],
JUN kinase binding [GO:0008432],
kinesin binding [GO:0019894],
mitogen-activated protein kinase kinase binding [GO:0031434],
mitogen-activated protein kinase kinase kinase binding [GO:0031435],
protein kinase binding [GO:0019901],
identical protein binding [GO:0042802],

Cellular Component:
nucleus [GO:0005634],
cytoplasm [GO:0005737],
endoplasmic reticulum membrane [GO:0005789],
cytosol [GO:0005829],
plasma membrane [GO:0005886],
mitochondrial membrane [GO:0031966],
dendritic growth cone [GO:0044294],
axonal growth cone [GO:0044295],
cell body [GO:0044297],
dentate gyrus mossy fiber [GO:0044302],
synapse [GO:0045202],
perinuclear region of cytoplasm [GO:0048471],
mitochondrion [GO:0005739],
endoplasmic reticulum [GO:0005783],
membrane [GO:0016020],
axon [GO:0030424],
dendrite [GO:0030425],
neuron projection [GO:0043005],