ARHGEF3
Rho guanine nucleotide exchange factor 3
Link to human orthologLink to mouse ortholog
Search for interactions with genes linked to senescence.
Status in senescence: Up-regulated | ||||
| Pubmed ID | Cell line | Tissue | Source | High-throughput |
| 31945125 | Primary astrocytes derived from brain | Human | YES | |
GO terms:
Biological Process:
G-protein coupled receptor signaling pathway [GO:0007186],
Rho protein signal transduction [GO:0007266],
positive regulation of Rho protein signal transduction [GO:0035025],
positive regulation of apoptotic process [GO:0043065],
regulation of small GTPase mediated signal transduction [GO:0051056],
regulation of Rho protein signal transduction [GO:0035023],
intracellular signal transduction [GO:0035556],
Molecular Function:
Rho guanyl-nucleotide exchange factor activity [GO:0005089],
protein binding [GO:0005515],
guanyl-nucleotide exchange factor activity [GO:0005085],
Cellular Component:
intracellular [GO:0005622],
cytosol [GO:0005829],
cytoplasm [GO:0005737],