ARHGEF17
Rho guanine nucleotide exchange factor 17
Link to human orthologLink to mouse ortholog
Search for interactions with genes linked to senescence.
Status in senescence: Down-regulated | ||||
| Pubmed ID | Cell line | Tissue | Source | High-throughput |
| 28844647 | BJ, WI-38, IMR-90, MRC-5, HFF-1, HCA2 | Skin, Lung | Human | YES |
GO terms:
Biological Process:
G-protein coupled receptor signaling pathway [GO:0007186],
actin cytoskeleton organization [GO:0030036],
positive regulation of apoptotic process [GO:0043065],
regulation of small GTPase mediated signal transduction [GO:0051056],
regulation of Rho protein signal transduction [GO:0035023],
Molecular Function:
guanyl-nucleotide exchange factor activity [GO:0005085],
Rho guanyl-nucleotide exchange factor activity [GO:0005089],
Cellular Component:
cytosol [GO:0005829],