ARHGEF10
Rho guanine nucleotide exchange factor 10
Link to human orthologLink to mouse ortholog
Search for interactions with genes linked to senescence.
Status in senescence: Down-regulated | ||||
| Pubmed ID | Cell line | Tissue | Source | High-throughput |
| 31945125 | Primary astrocytes derived from brain | Human | YES | |
GO terms:
Biological Process:
myelination in peripheral nervous system [GO:0022011],
actin cytoskeleton organization [GO:0030036],
regulation of Rho protein signal transduction [GO:0035023],
centrosome duplication [GO:0051298],
positive regulation of stress fiber assembly [GO:0051496],
mitotic spindle assembly [GO:0090307],
activation of GTPase activity [GO:0090630],
Molecular Function:
guanyl-nucleotide exchange factor activity [GO:0005085],
Rho guanyl-nucleotide exchange factor activity [GO:0005089],
protein binding [GO:0005515],
kinesin binding [GO:0019894],
Cellular Component:
centrosome [GO:0005813],
cytosol [GO:0005829],