Rho GTPase activating protein 42

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
28844647 BJ, WI-38, IMR-90, MRC-5, HFF, HCA154 Skin, Lung Human YES

GO terms:

Biological Process:
negative regulation of systemic arterial blood pressure [GO:0003085],
signal transduction [GO:0007165],
negative regulation of Rho protein signal transduction [GO:0035024],
activation of GTPase activity [GO:0090630],
negative regulation of vascular smooth muscle contraction [GO:1904694],

Molecular Function:
GTPase activator activity [GO:0005096],

Cellular Component:
cellular_component [GO:0005575],