Rho GTPase activating protein 4

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES

GO terms:

Biological Process:
cytoskeleton organization [GO:0007010],
Rho protein signal transduction [GO:0007266],
negative regulation of fibroblast migration [GO:0010764],
negative regulation of cell migration [GO:0030336],
negative regulation of axon extension [GO:0030517],
positive regulation of GTPase activity [GO:0043547],
regulation of small GTPase mediated signal transduction [GO:0051056],

Molecular Function:
GTPase activator activity [GO:0005096],
protein binding [GO:0005515],
Rac GTPase binding [GO:0048365],
identical protein binding [GO:0042802],

Cellular Component:
cytoplasm [GO:0005737],
Golgi apparatus [GO:0005794],
cytosol [GO:0005829],
microtubule [GO:0005874],
growth cone [GO:0030426],