ARHGAP33

Rho GTPase activating protein 33

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
28844647 BJ, WI-38, IMR-90, MRC-5, HFF, HCA192 Skin, Lung Human YES
30987592 MCF7 Breast Human YES
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
small GTPase mediated signal transduction [GO:0007264],
response to toxic substance [GO:0009636],
protein transport [GO:0015031],
positive regulation of GTPase activity [GO:0043547],
regulation of small GTPase mediated signal transduction [GO:0051056],
regulation of dendritic spine morphogenesis [GO:0061001],
signal transduction [GO:0007165],

Molecular Function:
GTPase activator activity [GO:0005096],
protein binding [GO:0005515],
protein kinase binding [GO:0019901],
phosphatidylinositol binding [GO:0035091],

Cellular Component:
cytoplasm [GO:0005737],
cytosol [GO:0005829],
plasma membrane [GO:0005886],
macromolecular complex [GO:0032991],
dendritic spine [GO:0043197],
membrane [GO:0016020],