Rho GTPase activating protein 32

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
28844647 BJ, WI-38, IMR-90, MRC-5, HFF-1, HCA2 Skin, Lung Human YES
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
small GTPase mediated signal transduction [GO:0007264],
positive regulation of GTPase activity [GO:0043547],
regulation of small GTPase mediated signal transduction [GO:0051056],
signal transduction [GO:0007165],
Rho protein signal transduction [GO:0007266],

Molecular Function:
GTPase activator activity [GO:0005096],
protein binding [GO:0005515],
phosphatidylinositol phosphate binding [GO:1901981],
phosphatidylinositol binding [GO:0035091],

Cellular Component:
Golgi membrane [GO:0000139],
fibrillar center [GO:0001650],
nucleoplasm [GO:0005654],
endoplasmic reticulum membrane [GO:0005789],
Golgi apparatus [GO:0005794],
cytosol [GO:0005829],
cell cortex [GO:0005938],
endosome membrane [GO:0010008],
postsynaptic density [GO:0014069],
actin cytoskeleton [GO:0015629],
dendritic spine [GO:0043197],
cytoplasm [GO:0005737],
endosome [GO:0005768],
endoplasmic reticulum [GO:0005783],
membrane [GO:0016020],
cell junction [GO:0030054],
cell projection [GO:0042995],
synapse [GO:0045202],