Rho GTPase activating protein 27

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945054 IMR-90 Human YES
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
receptor-mediated endocytosis [GO:0006898],
signal transduction [GO:0007165],
regulation of GTPase activity [GO:0043087],
positive regulation of GTPase activity [GO:0043547],
endocytosis [GO:0006897],

Molecular Function:
GTPase activator activity [GO:0005096],
SH3 domain binding [GO:0017124],

Cellular Component:
cytoplasm [GO:0005737],
membrane [GO:0016020],
endosome [GO:0005768],