ARHGAP25

Rho GTPase activating protein 25

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
30988157 IMR-90 Human YES
31945054 IMR-90 Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES
33296652 heart heart Human NO

GO terms:

Biological Process:
phagocytosis, engulfment [GO:0006911],
actin filament organization [GO:0007015],
signal transduction [GO:0007165],
regulation of small GTPase mediated signal transduction [GO:0051056],
negative regulation of small GTPase mediated signal transduction [GO:0051058],
activation of GTPase activity [GO:0090630],

Molecular Function:
GTPase activator activity [GO:0005096],

Cellular Component:
phagocytic cup [GO:0001891],
cytosol [GO:0005829],