ARHGAP21

Rho GTPase activating protein 21

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
Golgi organization [GO:0007030],
signal transduction [GO:0007165],
positive regulation of GTPase activity [GO:0043547],
regulation of small GTPase mediated signal transduction [GO:0051056],
Golgi localization [GO:0051645],
establishment of Golgi localization [GO:0051683],
maintenance of Golgi location [GO:0051684],
organelle transport along microtubule [GO:0072384],
regulation of endocytosis [GO:0030100],

Molecular Function:
GTPase activator activity [GO:0005096],
protein binding [GO:0005515],

Cellular Component:
Golgi membrane [GO:0000139],
Golgi apparatus [GO:0005794],
cytosol [GO:0005829],
plasma membrane [GO:0005886],
actin cytoskeleton [GO:0015629],
cell junction [GO:0030054],
cytoplasmic vesicle membrane [GO:0030659],
cytoplasm [GO:0005737],
cytoskeleton [GO:0005856],
membrane [GO:0016020],
cytoplasmic vesicle [GO:0031410],