ARHGAP12

Rho GTPase activating protein 12

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945125 Primary astrocytes derived from brain Human YES
31983656 MSC Human YES

GO terms:

Biological Process:
morphogenesis of an epithelial sheet [GO:0002011],
phagocytosis, engulfment [GO:0006911],
actin filament organization [GO:0007015],
signal transduction [GO:0007165],
regulation of GTPase activity [GO:0043087],
negative regulation of small GTPase mediated signal transduction [GO:0051058],
positive regulation of GTPase activity [GO:0043547],
regulation of small GTPase mediated signal transduction [GO:0051056],

Molecular Function:
molecular_function [GO:0003674],
GTPase activator activity [GO:0005096],

Cellular Component:
phagocytic cup [GO:0001891],
cytoplasm [GO:0005737],
cytosol [GO:0005829],