ABI2

abl interactor 2

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
27932314 Huh7 Human NO
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
cytoskeleton organization [GO:0007010],
actin polymerization or depolymerization [GO:0008154],
viral process [GO:0016032],
cell migration [GO:0016477],
Rac protein signal transduction [GO:0016601],
peptidyl-tyrosine phosphorylation [GO:0018108],
regulation of dendritic spine morphogenesis [GO:0061001],
lens fiber cell morphogenesis [GO:0070309],
positive regulation of Arp2/3 complex-mediated actin nucleation [GO:2000601],
nervous system development [GO:0007399],
learning or memory [GO:0007611],
dendrite development [GO:0016358],
camera-type eye development [GO:0043010],
zonula adherens assembly [GO:0045186],
postsynaptic actin cytoskeleton organization [GO:0098974],

Molecular Function:
DNA binding [GO:0003677],
protein binding [GO:0005515],
cytoskeletal adaptor activity [GO:0008093],
SH3 domain binding [GO:0017124],
kinase binding [GO:0019900],
ubiquitin protein ligase binding [GO:0031625],
identical protein binding [GO:0042802],
Rac GTPase binding [GO:0048365],
proline-rich region binding [GO:0070064],

Cellular Component:
nucleus [GO:0005634],
cytoplasm [GO:0005737],
cytosol [GO:0005829],
cytoskeleton [GO:0005856],
adherens junction [GO:0005912],
lamellipodium [GO:0030027],
SCAR complex [GO:0031209],
filopodium tip [GO:0032433],
dendritic spine [GO:0043197],
actin filament [GO:0005884],
cell junction [GO:0030054],
dendrite [GO:0030425],
cell projection [GO:0042995],
synapse [GO:0045202],
postsynaptic actin cytoskeleton [GO:0098871],
glutamatergic synapse [GO:0098978],