lemur tyrosine kinase 2

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945054 IMR-90 Human YES

GO terms:

Biological Process:
receptor recycling [GO:0001881],
protein phosphorylation [GO:0006468],
transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169],
multicellular organism development [GO:0007275],
nervous system development [GO:0007399],
axonogenesis [GO:0007409],
peptidyl-serine phosphorylation [GO:0018105],
peptidyl-threonine phosphorylation [GO:0018107],
peptidyl-tyrosine phosphorylation [GO:0018108],
endocytic recycling [GO:0032456],
negative regulation of phosphoprotein phosphatase activity [GO:0032515],
transferrin transport [GO:0033572],
positive regulation of kinase activity [GO:0033674],
early endosome to late endosome transport [GO:0045022],
protein autophosphorylation [GO:0046777],
axon guidance [GO:0007411],
phosphorylation [GO:0016310],
neurotrophin TRK receptor signaling pathway [GO:0048011],

Molecular Function:
protein serine/threonine kinase activity [GO:0004674],
transmembrane receptor protein tyrosine kinase activity [GO:0004714],
protein phosphatase inhibitor activity [GO:0004864],
protein binding [GO:0005515],
ATP binding [GO:0005524],
myosin VI binding [GO:0070853],
nucleotide binding [GO:0000166],
protein kinase activity [GO:0004672],
kinase activity [GO:0016301],
transferase activity [GO:0016740],

Cellular Component:
early endosome [GO:0005769],
Golgi apparatus [GO:0005794],
cytosol [GO:0005829],
integral component of plasma membrane [GO:0005887],
integral component of membrane [GO:0016021],
growth cone [GO:0030426],
neuronal cell body [GO:0043025],
receptor complex [GO:0043235],
perinuclear region of cytoplasm [GO:0048471],
recycling endosome [GO:0055037],
cytoplasm [GO:0005737],
membrane [GO:0016020],