ARFIP2

ADP ribosylation factor interacting protein 2

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945054 IMR-90 Human YES

GO terms:

Biological Process:
intracellular protein transport [GO:0006886],
autophagy [GO:0006914],
small GTPase mediated signal transduction [GO:0007264],
lamellipodium assembly [GO:0030032],
actin cytoskeleton organization [GO:0030036],
ruffle organization [GO:0031529],
regulation of Arp2/3 complex-mediated actin nucleation [GO:0034315],

Molecular Function:
protein binding [GO:0005515],
GTP binding [GO:0005525],
phospholipid binding [GO:0005543],
protein domain specific binding [GO:0019904],
GTP-dependent protein binding [GO:0030742],
identical protein binding [GO:0042802],
cadherin binding [GO:0045296],
Rac GTPase binding [GO:0048365],
phosphatidylinositol-4-phosphate binding [GO:0070273],

Cellular Component:
ruffle [GO:0001726],
cytoplasm [GO:0005737],
cytosol [GO:0005829],
plasma membrane [GO:0005886],
cell cortex [GO:0005938],
trans-Golgi network membrane [GO:0032588],
Golgi apparatus [GO:0005794],
membrane [GO:0016020],