abhydrolase domain containing 6, acylglycerol lipase

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
28844647 BJ, WI-38, IMR-90, MRC-5, HFF, HCA432 Skin, Lung Human YES

GO terms:

Biological Process:
phospholipid catabolic process [GO:0009395],
negative regulation of cell migration [GO:0030336],
acylglycerol catabolic process [GO:0046464],
positive regulation of lipid biosynthetic process [GO:0046889],
monoacylglycerol catabolic process [GO:0052651],
long term synaptic depression [GO:0060292],
regulation of endocannabinoid signaling pathway [GO:2000124],
lysobisphosphatidic acid metabolic process [GO:2001311],
lipid metabolic process [GO:0006629],

Molecular Function:
phospholipase activity [GO:0004620],
acylglycerol lipase activity [GO:0047372],
catalytic activity [GO:0003824],
hydrolase activity [GO:0016787],

Cellular Component:
mitochondrion [GO:0005739],
lysosomal membrane [GO:0005765],
plasma membrane [GO:0005886],
integral component of membrane [GO:0016021],
late endosome membrane [GO:0031902],
mitochondrial membrane [GO:0031966],
AMPA glutamate receptor complex [GO:0032281],
glutamatergic synapse [GO:0098978],
GABA-ergic synapse [GO:0098982],
integral component of postsynaptic membrane [GO:0099055],
lysosome [GO:0005764],
endosome [GO:0005768],
membrane [GO:0016020],