LGR5
leucine rich repeat containing G protein-coupled receptor 5
Link to human orthologLink to mouse ortholog
Search for interactions with genes linked to senescence.
Status in senescence: Down-regulated | ||||
Pubmed ID | Cell line | Tissue | Source | High-throughput |
30534415 | Epithelium | Mouse | NO |
GO terms:
Biological Process:
hair follicle development [GO:0001942],
G-protein coupled receptor signaling pathway [GO:0007186],
adenylate cyclase-activating G-protein coupled receptor signaling pathway [GO:0007189],
activation of adenylate cyclase activity [GO:0007190],
hormone-mediated signaling pathway [GO:0009755],
oocyte differentiation [GO:0009994],
regulation of cell proliferation [GO:0042127],
inner ear development [GO:0048839],
positive regulation of canonical Wnt signaling pathway [GO:0090263],
epithelial cell proliferation involved in renal tubule morphogenesis [GO:2001013],
signal transduction [GO:0007165],
Molecular Function:
transmembrane signaling receptor activity [GO:0004888],
G-protein coupled receptor activity [GO:0004930],
protein binding [GO:0005515],
G-protein coupled peptide receptor activity [GO:0008528],
protein-hormone receptor activity [GO:0016500],
Cellular Component:
plasma membrane [GO:0005886],
integral component of plasma membrane [GO:0005887],
trans-Golgi network membrane [GO:0032588],
Golgi apparatus [GO:0005794],
membrane [GO:0016020],
integral component of membrane [GO:0016021],