ARFGEF3
ARFGEF family member 3
Link to human orthologLink to mouse ortholog
Search for interactions with genes linked to senescence.
Status in senescence: Up-regulated | ||||
| Pubmed ID | Cell line | Tissue | Source | High-throughput |
| 28844647 | BJ, WI-38, IMR-90, MRC-5, HFF, HCA437 | Skin, Lung | Human | YES |
| 29548335 | Saos-2 | Human | YES | |
| 30988157 | IMR-90 | Human | YES | |
Status in senescence: Down-regulated | ||||
| Pubmed ID | Cell line | Tissue | Source | High-throughput |
| 29321003 | Primary bronchial epithelial cells derived from lung | Human | YES | |
GO terms:
Biological Process:
negative regulation of phosphatase activity [GO:0010923],
actin cytoskeleton organization [GO:0030036],
regulation of ARF protein signal transduction [GO:0032012],
Molecular Function:
ARF guanyl-nucleotide exchange factor activity [GO:0005086],
guanyl-nucleotide exchange factor activity [GO:0005085],
Cellular Component:
integral component of membrane [GO:0016021],
transport vesicle membrane [GO:0030658],
membrane [GO:0016020],
cytoplasmic vesicle [GO:0031410],