ARFGEF1

ADP ribosylation factor guanine nucleotide exchange factor 1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

GO terms:

Biological Process:
exocytosis [GO:0006887],
Golgi organization [GO:0007030],
endomembrane system organization [GO:0010256],
protein transport [GO:0015031],
negative regulation of actin filament polymerization [GO:0030837],
neuron projection development [GO:0031175],
regulation of ARF protein signal transduction [GO:0032012],
negative regulation of GTPase activity [GO:0034260],
positive regulation of GTPase activity [GO:0043547],
positive regulation of protein kinase B signaling [GO:0051897],
positive regulation of protein glycosylation in Golgi [GO:0090284],
positive regulation of wound healing [GO:0090303],
regulation of establishment of cell polarity [GO:2000114],

Molecular Function:
guanyl-nucleotide exchange factor activity [GO:0005085],
ARF guanyl-nucleotide exchange factor activity [GO:0005086],
GTPase activator activity [GO:0005096],
protein binding [GO:0005515],
myosin binding [GO:0017022],
protein kinase A regulatory subunit binding [GO:0034237],

Cellular Component:
Golgi membrane [GO:0000139],
nucleoplasm [GO:0005654],
nucleolus [GO:0005730],
Golgi apparatus [GO:0005794],
trans-Golgi network [GO:0005802],
cytosol [GO:0005829],
nuclear matrix [GO:0016363],
small nuclear ribonucleoprotein complex [GO:0030532],
perinuclear region of cytoplasm [GO:0048471],
nucleus [GO:0005634],
cytoplasm [GO:0005737],
membrane [GO:0016020],