LDB3

LIM domain binding 3

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29548335 Saos-2 Human YES
31945125 Primary astrocytes derived from brain Human YES
31915373 Hheart_LA_VS healthy Cardiomyocyte Human NO
31915373 Hheart_LV_VS healthy Cardiomyocyte Human NO

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945054 IMR-90 Human YES
33296652 heart heart Human NO

GO terms:

Biological Process:
heart development [GO:0007507],
actin cytoskeleton organization [GO:0030036],
sarcomere organization [GO:0045214],
muscle structure development [GO:0061061],

Molecular Function:
actin binding [GO:0003779],
protein kinase C binding [GO:0005080],
protein binding [GO:0005515],
cytoskeletal protein binding [GO:0008092],
metal ion binding [GO:0046872],
muscle alpha-actinin binding [GO:0051371],

Cellular Component:
stress fiber [GO:0001725],
cytoskeleton [GO:0005856],
adherens junction [GO:0005912],
Z disc [GO:0030018],
pseudopodium [GO:0031143],
filamentous actin [GO:0031941],
perinuclear region of cytoplasm [GO:0048471],
cytoplasm [GO:0005737],
cell projection [GO:0042995],