ARFGAP1

ADP ribosylation factor GTPase activating protein 1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945054 IMR-90 Human YES
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
ER to Golgi vesicle-mediated transport [GO:0006888],
retrograde vesicle-mediated transport, Golgi to ER [GO:0006890],
protein transport [GO:0015031],
regulation of endocytosis [GO:0030100],
regulation of ARF protein signal transduction [GO:0032012],
IRE1-mediated unfolded protein response [GO:0036498],
positive regulation of GTPase activity [GO:0043547],
vesicle-mediated transport [GO:0016192],

Molecular Function:
GTPase activator activity [GO:0005096],
protein binding [GO:0005515],
metal ion binding [GO:0046872],

Cellular Component:
Golgi membrane [GO:0000139],
cytosol [GO:0005829],
postsynaptic density [GO:0014069],
synapse [GO:0045202],
cytoplasm [GO:0005737],
Golgi apparatus [GO:0005794],