LAMP1

lysosomal associated membrane protein 1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31543366 WA09 Human YES
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
granzyme-mediated apoptotic signaling pathway [GO:0008626],
neutrophil degranulation [GO:0043312],
positive regulation of natural killer cell degranulation [GO:0043323],
positive regulation of natural killer cell mediated cytotoxicity [GO:0045954],
viral entry into host cell [GO:0046718],
autophagic cell death [GO:0048102],
protein stabilization [GO:0050821],
establishment of protein localization to organelle [GO:0072594],
Golgi to lysosome transport [GO:0090160],
regulation of organelle transport along microtubule [GO:1902513],
spermatogenesis [GO:0007283],

Molecular Function:
virus receptor activity [GO:0001618],
protein binding [GO:0005515],
enzyme binding [GO:0019899],
protein domain specific binding [GO:0019904],

Cellular Component:
cytoplasm [GO:0005737],
lysosome [GO:0005764],
lysosomal membrane [GO:0005765],
late endosome [GO:0005770],
multivesicular body [GO:0005771],
cytosol [GO:0005829],
plasma membrane [GO:0005886],
integral component of plasma membrane [GO:0005887],
external side of plasma membrane [GO:0009897],
endosome membrane [GO:0010008],
membrane [GO:0016020],
integral component of synaptic vesicle membrane [GO:0030285],
dendrite [GO:0030425],
late endosome membrane [GO:0031902],
azurophil granule membrane [GO:0035577],
sarcolemma [GO:0042383],
melanosome [GO:0042470],
neuronal cell body [GO:0043025],
cytolytic granule [GO:0044194],
autolysosome [GO:0044754],
perinuclear region of cytoplasm [GO:0048471],
phagolysosome membrane [GO:0061474],
extracellular exosome [GO:0070062],
alveolar lamellar body [GO:0097208],
ficolin-1-rich granule membrane [GO:0101003],
autophagosome membrane [GO:0000421],
endosome [GO:0005768],
vacuole [GO:0005773],
synaptic vesicle [GO:0008021],
cell surface [GO:0009986],
integral component of membrane [GO:0016021],
cytoplasmic vesicle [GO:0031410],
vesicle [GO:0031982],
phagocytic vesicle [GO:0045335],