ARC

activity regulated cytoskeleton associated protein

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
30988157 IMR-90 Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
31636448 HT-22 Mouse NO

GO terms:

Biological Process:
endocytosis [GO:0006897],
cytoskeleton organization [GO:0007010],
multicellular organism development [GO:0007275],
endoderm development [GO:0007492],
long-term memory [GO:0007616],
anterior/posterior pattern specification [GO:0009952],
cell migration [GO:0016477],
regulation of cell morphogenesis [GO:0022604],
regulation of neuronal synaptic plasticity [GO:0048168],
modulation of synaptic transmission [GO:0050804],
mRNA transport [GO:0051028],
protein homooligomerization [GO:0051260],
regulation of dendritic spine morphogenesis [GO:0061001],
regulation of long-term synaptic potentiation [GO:1900271],
regulation of long term synaptic depression [GO:1900452],
positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity [GO:2000969],
learning [GO:0007612],
long-term synaptic potentiation [GO:0060291],
dendritic spine morphogenesis [GO:0060997],

Molecular Function:
RNA binding [GO:0003723],
mRNA binding [GO:0003729],
actin binding [GO:0003779],
protein binding [GO:0005515],

Cellular Component:
cytoplasm [GO:0005737],
endosome [GO:0005768],
cytoskeleton [GO:0005856],
plasma membrane [GO:0005886],
actin cytoskeleton [GO:0015629],
membrane [GO:0016020],
cell junction [GO:0030054],
dendrite [GO:0030425],
cytoplasmic vesicle [GO:0031410],
cell projection [GO:0042995],
dendritic spine [GO:0043197],
membrane raft [GO:0045121],
synapse [GO:0045202],
postsynaptic membrane [GO:0045211],
neuronal ribonucleoprotein granule [GO:0071598],
postsynaptic density membrane [GO:0098839],
postsynaptic endosome [GO:0098845],
glutamatergic synapse [GO:0098978],
extracellular vesicle [GO:1903561],
acrosomal vesicle [GO:0001669],
cell cortex [GO:0005938],
early endosome membrane [GO:0031901],
neuronal cell body [GO:0043025],