LAMA2

laminin subunit alpha 2

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31964978 Primary astrocytes derived from brain Mouse YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
28844647 BJ, WI-38, IMR-90, MRC-5, HFF-1, HCA2 Skin, Lung Human YES
32029712 Primary synovial fibroblast Human YES

GO terms:

Biological Process:
cell adhesion [GO:0007155],
axon guidance [GO:0007411],
muscle organ development [GO:0007517],
animal organ morphogenesis [GO:0009887],
tissue development [GO:0009888],
Schwann cell differentiation [GO:0014037],
regulation of cell adhesion [GO:0030155],
extracellular matrix organization [GO:0030198],
regulation of cell migration [GO:0030334],
positive regulation of synaptic transmission, cholinergic [GO:0032224],
maintenance of blood-brain barrier [GO:0035633],
regulation of embryonic development [GO:0045995],

Molecular Function:
receptor binding [GO:0005102],
structural molecule activity [GO:0005198],
extracellular matrix structural constituent [GO:0005201],

Cellular Component:
extracellular region [GO:0005576],
basement membrane [GO:0005604],
neuromuscular junction [GO:0031594],
sarcolemma [GO:0042383],
synaptic cleft [GO:0043083],
dendritic spine [GO:0043197],