ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
Link to human orthologLink to mouse ortholog
Search for interactions with genes linked to senescence.
Status in senescence: Up-regulated | ||||
| Pubmed ID | Cell line | Tissue | Source | High-throughput |
| 29548335 | Saos-2 | Human | YES | |
| 31155496 | Primary β cells derived from pancreas | Mouse | YES | |
Status in senescence: Down-regulated | ||||
| Pubmed ID | Cell line | Tissue | Source | High-throughput |
| 31945125 | Primary astrocytes derived from brain | Human | YES | |
GO terms:
Biological Process:
signal transduction [GO:0007165],
positive regulation of GTPase activity [GO:0043547],
regulation of small GTPase mediated signal transduction [GO:0051056],
Molecular Function:
GTPase activator activity [GO:0005096],
phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547],
metal ion binding [GO:0046872],
Cellular Component:
cytosol [GO:0005829],
cytoplasm [GO:0005737],