ARAP2

ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29548335 Saos-2 Human YES
31155496 Primary β cells derived from pancreas Mouse YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
signal transduction [GO:0007165],
positive regulation of GTPase activity [GO:0043547],
regulation of small GTPase mediated signal transduction [GO:0051056],

Molecular Function:
GTPase activator activity [GO:0005096],
phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547],
metal ion binding [GO:0046872],

Cellular Component:
cytosol [GO:0005829],
cytoplasm [GO:0005737],