aquarius intron-binding spliceosomal factor

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
mRNA splicing, via spliceosome [GO:0000398],
transcription-coupled nucleotide-excision repair [GO:0006283],
mRNA processing [GO:0006397],
RNA splicing [GO:0008380],

Molecular Function:
RNA binding [GO:0003723],
RNA helicase activity [GO:0003724],
mRNA binding [GO:0003729],
protein binding [GO:0005515],
ATP binding [GO:0005524],
nucleotide binding [GO:0000166],
helicase activity [GO:0004386],
hydrolase activity [GO:0016787],

Cellular Component:
nucleus [GO:0005634],
nucleoplasm [GO:0005654],
spliceosomal complex [GO:0005681],
membrane [GO:0016020],
U2-type catalytic step 2 spliceosome [GO:0071007],
catalytic step 2 spliceosome [GO:0071013],