lysine methyltransferase 5C

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES

GO terms:

Biological Process:
DNA repair [GO:0006281],
histone H4-K20 trimethylation [GO:0034773],
positive regulation of isotype switching [GO:0045830],
positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034],
chromatin organization [GO:0006325],
histone methylation [GO:0016571],
methylation [GO:0032259],

Molecular Function:
chromatin binding [GO:0003682],
protein binding [GO:0005515],
histone binding [GO:0042393],
histone methyltransferase activity (H4-K20 specific) [GO:0042799],
metal ion binding [GO:0046872],
S-adenosyl-L-methionine binding [GO:1904047],
methyltransferase activity [GO:0008168],
transferase activity [GO:0016740],

Cellular Component:
condensed nuclear chromosome, centromeric region [GO:0000780],
nucleus [GO:0005634],
nucleoplasm [GO:0005654],
nuclear heterochromatin [GO:0005720],
pericentric heterochromatin [GO:0005721],
chromosome [GO:0005694],