aquaporin 3 (Gill blood group)

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES
29548335 Saos-2, Li-Fraumeni Human YES
31945125 Primary astrocytes derived from brain Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
31895587 Spleen Mouse NO
31945054 IMR-90 Human YES

GO terms:

Biological Process:
positive regulation of immune system process [GO:0002684],
renal water homeostasis [GO:0003091],
water transport [GO:0006833],
glycerol transport [GO:0015793],
response to retinoic acid [GO:0032526],
response to vitamin D [GO:0033280],
odontogenesis [GO:0042476],
regulation of keratinocyte differentiation [GO:0045616],
response to calcium ion [GO:0051592],
renal water absorption [GO:0070295],
cellular response to hypoxia [GO:0071456],
urea transmembrane transport [GO:0071918],
cellular response to oxygen-glucose deprivation [GO:0090650],
urea transport [GO:0015840],
transmembrane transport [GO:0055085],

Molecular Function:
urea transmembrane transporter activity [GO:0015204],
water channel activity [GO:0015250],
glycerol channel activity [GO:0015254],
channel activity [GO:0015267],

Cellular Component:
nucleoplasm [GO:0005654],
cytoplasm [GO:0005737],
plasma membrane [GO:0005886],
cell-cell junction [GO:0005911],
integral component of membrane [GO:0016021],
basolateral plasma membrane [GO:0016323],
integral component of plasma membrane [GO:0005887],
membrane [GO:0016020],