APRT

adenine phosphoribosyltransferase

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945054 IMR-90 Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES

GO terms:

Biological Process:
purine ribonucleoside salvage [GO:0006166],
adenine salvage [GO:0006168],
lactation [GO:0007595],
grooming behavior [GO:0007625],
cellular response to insulin stimulus [GO:0032869],
purine-containing compound salvage [GO:0043101],
neutrophil degranulation [GO:0043312],
AMP salvage [GO:0044209],
nucleoside metabolic process [GO:0009116],
adenine metabolic process [GO:0046083],

Molecular Function:
adenine binding [GO:0002055],
adenine phosphoribosyltransferase activity [GO:0003999],
AMP binding [GO:0016208],
transferase activity [GO:0016740],
transferase activity, transferring glycosyl groups [GO:0016757],

Cellular Component:
extracellular region [GO:0005576],
nucleoplasm [GO:0005654],
cytoplasm [GO:0005737],
cytosol [GO:0005829],
secretory granule lumen [GO:0034774],
extracellular exosome [GO:0070062],