ABHD3
abhydrolase domain containing 3, phospholipase
Link to human orthologLink to mouse ortholog
Search for interactions with genes linked to senescence.
Status in senescence: Up-regulated | ||||
| Pubmed ID | Cell line | Tissue | Source | High-throughput |
| 27323328 | Saos-2,H1299, HT18, MCF7, MDA-MB-231, Li-Fraumeni | Human | YES | |
| 29548335 | Saos-2 | Human | YES | |
Status in senescence: Down-regulated | ||||
| Pubmed ID | Cell line | Tissue | Source | High-throughput |
| 31945125 | Primary astrocytes derived from brain | Human | YES | |
GO terms:
Biological Process:
lipid metabolic process [GO:0006629],
cellular lipid metabolic process [GO:0044255],
phosphatidylcholine metabolic process [GO:0046470],
medium-chain fatty acid biosynthetic process [GO:0051792],
medium-chain fatty acid catabolic process [GO:0051793],
phosphatidylcholine biosynthetic process [GO:0006656],
Molecular Function:
phospholipase A2 activity [GO:0004623],
acetylesterase activity [GO:0008126],
phosphatidylcholine 1-acylhydrolase activity [GO:0008970],
hydrolase activity [GO:0016787],
short-chain carboxylesterase activity [GO:0034338],
acylglycerol lipase activity [GO:0047372],
carboxylic ester hydrolase activity [GO:0052689],
phosphatidylserine 1-acylhydrolase activity [GO:0052739],
1-acyl-2-lysophosphatidylserine acylhydrolase activity [GO:0052740],
Cellular Component:
cellular_component [GO:0005575],
membrane [GO:0016020],
integral component of membrane [GO:0016021],
plasma membrane [GO:0005886],