APOL1
apolipoprotein L1
Link to human orthologSearch for interactions with genes linked to senescence.
Status in senescence: Up-regulated | ||||
| Pubmed ID | Cell line | Tissue | Source | High-throughput |
| 12837283 | NHOK | Human | NO | |
| 29321003 | Primary bronchial epithelial cells derived from lung | Human | YES | |
| 29548335 | Saos-2 | Human | YES | |
| 31945125 | Primary astrocytes derived from brain | Human | YES | |
Status in senescence: Down-regulated | ||||
| Pubmed ID | Cell line | Tissue | Source | High-throughput |
| 31945054 | IMR-90 | Human | YES | |
GO terms:
Biological Process:
lipid transport [GO:0006869],
receptor-mediated endocytosis [GO:0006898],
cholesterol metabolic process [GO:0008203],
lipoprotein metabolic process [GO:0042157],
post-translational protein modification [GO:0043687],
cellular protein metabolic process [GO:0044267],
innate immune response [GO:0045087],
cytolysis by host of symbiont cells [GO:0051838],
chloride transmembrane transport [GO:1902476],
Molecular Function:
chloride channel activity [GO:0005254],
protein binding [GO:0005515],
lipid binding [GO:0008289],
Cellular Component:
extracellular region [GO:0005576],
extracellular space [GO:0005615],
endoplasmic reticulum lumen [GO:0005788],
intrinsic component of membrane [GO:0031224],
very-low-density lipoprotein particle [GO:0034361],
high-density lipoprotein particle [GO:0034364],
blood microparticle [GO:0072562],