apolipoprotein D

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
12837283 Primary normal oral keratinocytes Oral Human NO
30988157 IMR-90 Human YES
31915373 Hheart_LV_VS healthy Cardiomyocyte Human NO

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
31915373 Hheart_LA_VS healthy Smooth muscle cell Human NO

GO terms:

Biological Process:
response to reactive oxygen species [GO:0000302],
angiogenesis [GO:0001525],
glucose metabolic process [GO:0006006],
lipid metabolic process [GO:0006629],
lipid transport [GO:0006869],
brain development [GO:0007420],
aging [GO:0007568],
negative regulation of platelet-derived growth factor receptor signaling pathway [GO:0010642],
peripheral nervous system axon regeneration [GO:0014012],
tissue regeneration [GO:0042246],
negative regulation of protein import into nucleus [GO:0042308],
response to drug [GO:0042493],
negative regulation of smooth muscle cell proliferation [GO:0048662],
response to axon injury [GO:0048678],
negative regulation of focal adhesion assembly [GO:0051895],
negative regulation of lipoprotein lipid oxidation [GO:0060588],
negative regulation of monocyte chemotactic protein-1 production [GO:0071638],
negative regulation of cytokine production involved in inflammatory response [GO:1900016],
negative regulation of smooth muscle cell-matrix adhesion [GO:2000098],
negative regulation of T cell migration [GO:2000405],

Molecular Function:
lipid transporter activity [GO:0005319],
protein binding [GO:0005515],
cholesterol binding [GO:0015485],
lipid binding [GO:0008289],

Cellular Component:
extracellular region [GO:0005576],
extracellular space [GO:0005615],
cytoplasm [GO:0005737],
endoplasmic reticulum [GO:0005783],
cytosolic ribosome [GO:0022626],
dendrite [GO:0030425],
neuronal cell body [GO:0043025],
perinuclear region of cytoplasm [GO:0048471],
extracellular exosome [GO:0070062],
intracellular [GO:0005622],