apolipoprotein C3

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945054 IMR-90 Human YES

GO terms:

Biological Process:
retinoid metabolic process [GO:0001523],
triglyceride metabolic process [GO:0006641],
G-protein coupled receptor signaling pathway [GO:0007186],
negative regulation of triglyceride catabolic process [GO:0010897],
negative regulation of very-low-density lipoprotein particle remodeling [GO:0010903],
negative regulation of very-low-density lipoprotein particle clearance [GO:0010916],
negative regulation of high-density lipoprotein particle clearance [GO:0010987],
negative regulation of low-density lipoprotein particle clearance [GO:0010989],
triglyceride catabolic process [GO:0019433],
regulation of Cdc42 protein signal transduction [GO:0032489],
cholesterol efflux [GO:0033344],
phospholipid efflux [GO:0033700],
chylomicron remodeling [GO:0034371],
high-density lipoprotein particle remodeling [GO:0034375],
chylomicron assembly [GO:0034378],
very-low-density lipoprotein particle assembly [GO:0034379],
chylomicron remnant clearance [GO:0034382],
lipoprotein metabolic process [GO:0042157],
cholesterol homeostasis [GO:0042632],
reverse cholesterol transport [GO:0043691],
negative regulation of fatty acid biosynthetic process [GO:0045717],
negative regulation of lipid metabolic process [GO:0045833],
negative regulation of receptor-mediated endocytosis [GO:0048261],
negative regulation of lipid catabolic process [GO:0050995],
negative regulation of lipoprotein lipase activity [GO:0051005],
negative regulation of cholesterol import [GO:0060621],
triglyceride homeostasis [GO:0070328],
lipid metabolic process [GO:0006629],
triglyceride mobilization [GO:0006642],
lipid transport [GO:0006869],
cholesterol metabolic process [GO:0008203],
positive regulation of triglyceride biosynthetic process [GO:0010867],
lipid catabolic process [GO:0016042],
lipoprotein transport [GO:0042953],
response to peptide hormone [GO:0043434],
cellular response to glucose stimulus [GO:0071333],
negative regulation of oxidative phosphorylation [GO:0090324],

Molecular Function:
phospholipid binding [GO:0005543],
cholesterol binding [GO:0015485],
enzyme regulator activity [GO:0030234],
lipase inhibitor activity [GO:0055102],
high-density lipoprotein particle receptor binding [GO:0070653],
lipid binding [GO:0008289],

Cellular Component:
extracellular region [GO:0005576],
extracellular space [GO:0005615],
early endosome [GO:0005769],
very-low-density lipoprotein particle [GO:0034361],
intermediate-density lipoprotein particle [GO:0034363],
spherical high-density lipoprotein particle [GO:0034366],
chylomicron [GO:0042627],
extracellular exosome [GO:0070062],
cytosol [GO:0005829],