KCND3

potassium voltage-gated channel subfamily D member 3

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29548335 Saos-2 Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945054 IMR-90 Human YES
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
potassium ion transport [GO:0006813],
regulation of ion transmembrane transport [GO:0034765],
protein homooligomerization [GO:0051260],
cardiac conduction [GO:0061337],
potassium ion transmembrane transport [GO:0071805],
membrane repolarization [GO:0086009],
membrane repolarization during cardiac muscle cell action potential [GO:0086013],
regulation of heart rate by cardiac conduction [GO:0086091],
potassium ion export across plasma membrane [GO:0097623],
membrane repolarization during ventricular cardiac muscle cell action potential [GO:0098915],
ventricular cardiac muscle cell membrane repolarization [GO:0099625],
ion transport [GO:0006811],
transmembrane transport [GO:0055085],
cellular response to BMP stimulus [GO:0071773],
potassium ion import across plasma membrane [GO:1990573],

Molecular Function:
voltage-gated potassium channel activity [GO:0005249],
A-type (transient outward) potassium channel activity [GO:0005250],
protein binding [GO:0005515],
ion channel binding [GO:0044325],
metal ion binding [GO:0046872],
voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization [GO:0086008],
voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization [GO:1902282],
ion channel activity [GO:0005216],
voltage-gated ion channel activity [GO:0005244],
potassium channel activity [GO:0005267],

Cellular Component:
plasma membrane [GO:0005886],
voltage-gated potassium channel complex [GO:0008076],
postsynaptic density [GO:0014069],
integral component of membrane [GO:0016021],
dendrite [GO:0030425],
sarcolemma [GO:0042383],
neuronal cell body [GO:0043025],
dendritic spine [GO:0043197],
postsynaptic membrane [GO:0045211],
GABA-ergic synapse [GO:0098982],
integral component of postsynaptic specialization membrane [GO:0099060],
integral component of plasma membrane [GO:0005887],
caveola [GO:0005901],
membrane [GO:0016020],
potassium channel complex [GO:0034705],
cell projection [GO:0042995],
neuron projection [GO:0043005],
perinuclear endoplasmic reticulum [GO:0097038],