KCND2

potassium voltage-gated channel subfamily D member 2

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29548335 Saos-2 Human YES
30988157 IMR-90 Human YES

GO terms:

Biological Process:
action potential [GO:0001508],
chemical synaptic transmission [GO:0007268],
neuronal action potential [GO:0019228],
sensory perception of pain [GO:0019233],
regulation of ion transmembrane transport [GO:0034765],
locomotor rhythm [GO:0045475],
protein homooligomerization [GO:0051260],
regulation of postsynaptic membrane potential [GO:0060078],
cardiac conduction [GO:0061337],
cellular response to hypoxia [GO:0071456],
potassium ion transmembrane transport [GO:0071805],
ion transport [GO:0006811],
potassium ion transport [GO:0006813],
transmembrane transport [GO:0055085],
cardiac muscle cell action potential [GO:0086001],

Molecular Function:
voltage-gated potassium channel activity [GO:0005249],
A-type (transient outward) potassium channel activity [GO:0005250],
protein binding [GO:0005515],
metal ion binding [GO:0046872],
voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1905030],
ion channel activity [GO:0005216],
voltage-gated ion channel activity [GO:0005244],
potassium channel activity [GO:0005267],
macromolecular complex binding [GO:0044877],

Cellular Component:
plasma membrane [GO:0005886],
integral component of plasma membrane [GO:0005887],
voltage-gated potassium channel complex [GO:0008076],
postsynaptic density [GO:0014069],
integral component of membrane [GO:0016021],
intrinsic component of plasma membrane [GO:0031226],
neuronal cell body membrane [GO:0032809],
dendritic spine [GO:0043197],
perikaryon [GO:0043204],
plasma membrane raft [GO:0044853],
postsynaptic membrane [GO:0045211],
glutamatergic synapse [GO:0098978],
GABA-ergic synapse [GO:0098982],
integral component of postsynaptic specialization membrane [GO:0099060],
caveola [GO:0005901],
membrane [GO:0016020],
cell junction [GO:0030054],
T-tubule [GO:0030315],
dendrite [GO:0030425],
potassium channel complex [GO:0034705],
sarcolemma [GO:0042383],
cell projection [GO:0042995],
neuron projection [GO:0043005],
neuronal cell body [GO:0043025],
synapse [GO:0045202],
perinuclear endoplasmic reticulum [GO:0097038],
integral component of postsynaptic membrane [GO:0099055],